2025 NIH Workshop on Prenatal Dietary Supplements

Day 1: Monday, June 30

Assessing the Current State of Prenatal Supplement Use

Day 2: Tuesday, July 1

Evaluating Evidence and Setting Research Directions

9:30 AM — 9:45 AM

Welcome and Opening Remarks

Workshop goals, objectives, and structure.

Andrew A. Bremer, M.D., Ph.D., M.A.S.

Jaime Gahche, Ph.D., M.P.H.

9:45 AM — 10:05 AM

Keynote Presentation

Overview of the current state of prenatal supplement use and its critical importance.

Nicole Marshall, M.D., M.C.R., IBCLC, FACOG, FABM

10:05 AM — 12:00 PM

Session 1: Nutrient Contributions to Intakes from Prenatals and Prenatal Supplement Products

Discuss prenatal supplements' contributions to total nutrient intakes for pregnant women (NHANES, other large cohorts, and surveys) and review of types of prenatal dietary supplements available in the U.S. market and their nutrient content.

Regan Bailey, Ph.D.

Alexandra E. Cowan-Pyle, Ph.D.

Katherine Sauder, Ph.D.

Edwina Wambogo, Ph.D., M.P.H., R.D.

Laura M. Borgelt, Pharm.D., MBA, FCCP, BCPS

12:00 PM — 12:30 PM

Panel: Session 1 Discussion

Regan Bailey, Ph.D.

Alexandra E. Cowan-Pyle, Ph.D.

Katherine Sauder, Ph.D.

Edwina Wambogo, Ph.D., M.P.H., R.D.

Laura M. Borgelt, Pharm.D., MBA, FCCP, BCPS

12:30 PM — 1:30 PM

Lunch (on your own)

1:30 PM — 2:15 PM

Session 2: Nutrient Requirements During Pregnancy, including Special Population Groups

Micronutrient requirements during pregnancy and current evidence for optimal outcomes.

Emily R. Smith, ScD, MPH

2:15 PM — 3:00 PM

Panel: Challenges in Formulating Prenatals

Discuss formulation considerations for prenatal supplements (over-supplementation, contaminants, interactions).

Andrea Wong, Ph.D.

Susan H. Mitmesser, Ph.D.

3:00 PM — 3:15 PM

Break

3:15 PM — 3:45 PM

Panel Discussion

Key insights and Q&A with Day 1 presenters.

Regan Bailey, Ph.D.

Alexandra E. Cowan-Pyle, Ph.D.

Katherine Sauder, Ph.D.

Edwina Wambogo, Ph.D., M.P.H., R.D.

Laura M. Borgelt, Pharm.D., MBA, FCCP, BCPS

Emily R. Smith, ScD, MPH

Andrea Wong, Ph.D.

Susan H. Mitmesser, Ph.D.

4:00 PM

Adjourn

9:30 AM — 9:45 AM

Welcome and Introduction to Day 2

Jaime Gahche, Ph.D., M.P.H.

Session 4: Micronutrient Focus

Identify critical micronutrients and evaluate optimal ranges in prenatal supplements.

James L. Mills, M.D., M.S.

Julia Finkelstein, Sc.D., M.P.H.

9:45 AM — 10:45 AM

Session 4a: One-Carbon Metabolism Micronutrients

Folate, B12, and choline: Evidence on roles and optimal levels.

Krista Crider, Ph.D.

Yvonne Lamers, Ph.D.

Steven Zeisel, Ph.D.

10:45 AM — 11:00 AM

Break

11:00 AM — 12:00 PM

Session 4b: Minerals (and Vitamin D)

Iron, iodine, calcium, and magnesium: Evidence review and gaps.

Kimberly O’Brien, Ph.D.

Elizabeth N. Pearce, M.D., M.Sc.

Michael K. Georgieff, M.D.

12:00 PM — 12:30 PM

Panel: Session 4a and 4b Discussion

Yvonne Lamers, Ph.D.

Steven Zeisel, Ph.D.

Kimberly O’Brien, Ph.D.

Elizabeth N. Pearce, M.D., M.Sc.

Michael K. Georgieff, M.D.

12:30 PM — 1:30 PM

Lunch (on your own)

1:30 PM — 1:50 PM

Session 4c: Omega-3 Fatty Acids

Explore the evidence for Omega-3 fatty acids in supporting maternal and fetal health and consider optimal Omega-3 levels in prenatal products.

Emily Oken, M.D.

1:50 PM — 2:10 PM

Session 4d: Lutein/Zeaxanthin

Elizabeth J. Johnson, Ph.D., FASN, FACN, FICS

2:10 PM — 2:30 PM

Panel: Session 4c & 4d Discussion

Emily Oken, M.D.

Elizabeth J. Johnson, Ph.D., FASN, FACN, FICS

2:30 PM — 2:45 PM

Break

2:45 PM — 3:15 PM

Session 5: Research Needs and Data Gaps

Identify priority areas for research, including data collection on use patterns, biomarkers, and outcomes.

Patrick J. Stover, Ph.D.

3:15 PM — 4:15 PM

Breakout Groups: Research Recommendations

Small group discussions to draft recommendations for further research and data collection.

4:15 PM — 4:30 PM

Closing Remarks

Final summary, outcomes, and next steps.

Jaime Gahche, Ph.D., M.P.H.

4:30 PM

Adjourn

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