2025 NIH Workshop on Prenatal Dietary Supplements

Day 1: Monday, June 30

Assessing the Current State of Prenatal Supplement Use

Day 2: Tuesday, July 1

Evaluating Evidence and Setting Research Directions

9:30 AM — 9:45 AM

Welcome and Opening Remarks

Workshop goals, objectives, and structure.

Andrew A. Bremer, M.D., Ph.D., MAS

Jaime Gahche, Ph.D., MPH

9:45 AM — 10:05 AM

Keynote Presentation

Overview of the current state of prenatal supplement use and its critical importance.

Nicole Marshall, M.D., FACOG

10:05 AM — 12:00 PM

Session 1: Nutrient Contributions to Intakes from Prenatals and Prenatal Supplement Products

Discuss prenatal supplements' contributions to total nutrient intakes for pregnant women (NHANES, other large cohorts, and surveys) and review of types of prenatal dietary supplements available in the U.S. market and their nutrient content.

Jill Reedy, Ph.D., MPH, RDN

Annina Burns, Ph.D., RD

Regan Bailey, Ph.D., MPH

Alexandra E. Cowan-Pyle, Ph.D.

Katherine Sauder, Ph.D.

Edwina Wambogo, Ph.D., MPH, RD

Laura M. Borgelt, Pharm.D., MBA

12:00 PM — 12:30 PM

Panel: Session 1 Discussion

Regan Bailey, Ph.D., MPH

Alexandra E. Cowan-Pyle, Ph.D.

Katherine Sauder, Ph.D.

Edwina Wambogo, Ph.D., MPH, RD

Laura M. Borgelt, Pharm.D., MBA

12:30 PM — 1:30 PM

Lunch (on your own)

1:30 PM — 2:15 PM

Session 2: Nutrient Requirements During Pregnancy, including Special Population Groups

Micronutrient requirements during pregnancy and current evidence for optimal outcomes.

Sharon Ross, Ph.D., MPH

Bramaramba (Brama) Kowtha, MS, RDN, LDN

Emily R. Smith, ScD, MPH

2:15 PM — 3:00 PM

Session 3: Challenges in Formulating Prenatal Dietary Supplements

Discuss formulation considerations for prenatal supplements (over-supplementation, contaminants, interactions).

Johanna Dwyer, D.Sc., RD

Andrea Wong, Ph.D.

Susan H. Mitmesser, Ph.D.

3:00 PM — 3:15 PM

Break

3:15 PM — 3:45 PM

Panel Discussion

Key insights and Q&A with Day 1 presenters.

Regan Bailey, Ph.D., MPH

Alexandra E. Cowan-Pyle, Ph.D.

Katherine Sauder, Ph.D.

Edwina Wambogo, Ph.D., MPH, RD

Laura M. Borgelt, Pharm.D., MBA

Emily R. Smith, ScD, MPH

Andrea Wong, Ph.D.

Susan H. Mitmesser, Ph.D.

4:00 PM

Adjourn

9:30 AM — 9:35 AM

Welcome and Introduction to Day 2

Jaime Gahche, Ph.D., MPH

Session 4: Micronutrient Focus

Identify critical micronutrients and evaluate optimal ranges in prenatal supplements.

James L. Mills, M.D., MS

Julia L. Finkelstein, Sc.D., SM, MPH

9:35 AM — 10:35 AM

Session 4a: One-Carbon Metabolism Micronutrients

Folate, B12, and choline: Evidence on roles and optimal levels.

Krista Crider, Ph.D.

Yvonne Lamers, Ph.D.

Steven Zeisel, M.D., Ph.D.

10:35 AM — 10:50 AM

Break

10:50 AM — 11:50 AM

Session 4b: Minerals (and Vitamin D)

Iron, iodine, calcium, and magnesium: Evidence review and gaps.

Kimberly O’Brien, Ph.D.

Elizabeth N. Pearce, M.D., M.Sc.

Michael K. Georgieff, M.D.

11:50 AM — 12:30 PM

Session 4c: Omega-3 Fatty Acids

Lutein in supporting maternal and fetal health.

Emily Oken, M.D.

Elizabeth J. Johnson, Ph.D., FASN, FACN, FICS

12:30 PM — 1:00 PM

Panel Discussion

Yvonne Lamers, Ph.D.

Steven Zeisel, M.D., Ph.D.

Kimberly O’Brien, Ph.D.

Elizabeth N. Pearce, M.D., M.Sc.

Michael K. Georgieff, M.D.

Emily Oken, M.D.

Krista Crider, Ph.D.

1:00 PM — 2:00 PM

Lunch (on your own)

2:00 PM — 2:30 PM

Session 5: Research Needs and Data Gaps

Identify priority areas for research, including data collection on use patterns, biomarkers, and outcomes.

Patrick J. Stover, Ph.D.

2:30 PM — 2:45 PM

Break

2:45 PM — 4:15 PM

Breakout Groups: Research Recommendations

In-person: Small group discussions to draft recommendations for further research and data collection

Virtual: Group collaboration exercise

4:15 PM — 4:35 PM

Closing Remarks

Final summary, outcomes, and next steps.

Jaime Gahche, Ph.D., MPH

4:35 PM

Adjourn